Context‐dependent regulation of Th17‐associated genes and IFNγ expression by the transcription factor NFAT5
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چکیده
منابع مشابه
Context-dependent regulation of Th17-associated genes and IFNγ expression by the transcription factor NFAT5
Stress-activated transcription factors influence T-cell function in different physiopathologic contexts. NFAT5, a relative of nuclear factor κB and the calcineurin-activated NFATc transcription factors, protects mammalian cells from hyperosmotic stress caused by the elevation of extracellular sodium levels. In T cells exposed to hypernatremia, NFAT5 not only induces osmoprotective gene products...
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ژورنال
عنوان ژورنال: Immunology & Cell Biology
سال: 2016
ISSN: 0818-9641,1440-1711
DOI: 10.1038/icb.2016.69